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Total cerebellar volume (excluding Crus I vermis)

PTPA · rs3118634

What the study found

Who was studied 33,265 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0348 lower (95% confidence interval 0.024-0.046); p = 2 × 10−10.

Where it sits Chromosome 9, band 9q34.11 — in the 3′ untranslated region of PTPA.

What each result means

A/A Two copies of the version the research linked to Total cerebellar volume (excluding Crus I vermis). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Total cerebellar volume (excluding Crus I vermis). That is a smaller link than two copies.
G/G No copy of the version the research linked to Total cerebellar volume (excluding Crus I vermis). This is the starting point the study compared everyone against.
Source

Questions about rs3118634

What is rs3118634?

rs3118634 is a single position in the genome, in or near the PTPA gene. Published research associates it with total cerebellar volume (excluding crus i vermis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3118634 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3118634 come from?

GWAS Catalog, Molecular psychiatry 2022, PMID:35079123. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total cerebellar volume (excluding Crus I vermis) (rs3118634). MyGeneLog™. https://www.mygenelog.com/variants/rs3118634

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