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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 7,540 European ancestry individuals; replicated in 3,224 European, Greater Middle Eastern or South Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0166 higher (95% confidence interval 0.012-0.021); p = 7 × 10−14.
How common The C allele had a frequency of about 90% in the people studied.
Where it sits Chromosome 1, band 1p36.11 — between genes, 25.3 kb from RUNX3.
What each result means
C/CTwo copies of the version the research linked to Biantennary glycan levels (multivariate analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Biantennary glycan levels (multivariate analysis). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Biantennary glycan levels (multivariate analysis). This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40593539 · open access
Questions about rs311432
What is rs311432?
rs311432 is a single position in the genome, in or near the near RUNX3 gene. Published research associates it with biantennary glycan levels (multivariate analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs311432 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs311432 come from?
GWAS Catalog, Nature communications 2025, PMID:40593539. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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