Standard

height (mean, inv-normal transformed)

near PRKG2 · rs3114140

Where this position leads

Condition: Height

rs3114140 Condition: Height Height Condition rs3114140 rs3114140 near PRKG2

What the study found

Who was studied 119,012 African American or Afro-Caribbean individuals, 57,810 Hispanic or Latin American individuals, 6,384 East Asian ancestry individuals, 424,305 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0809 lower (95% confidence interval 0.074-0.088); p = 2 × 10−105.

How common The G allele had a frequency of about 62% in the people studied.

Where it sits Chromosome 4, band 4q21.21 — between genes, 28.1 kb from PRKG2.

What each result means

A/A No copy of the version the research linked to height (mean, inv-normal transformed). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to height (mean, inv-normal transformed). That is a smaller link than two copies.
G/G Two copies of the version the research linked to height (mean, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3114140

What is rs3114140?

rs3114140 is a single position in the genome, in or near the near PRKG2 gene. Published research associates it with height (mean, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3114140 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs3114140 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3114140 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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height (mean, inv-normal transformed) (rs3114140). MyGeneLog™. https://www.mygenelog.com/variants/rs3114140

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