Standard

Triglycerides

SLC22A3 · rs3105749

Where this position leads

Condition: High Triglycerides

rs3105749 Condition: High Triglycerides High Triglycerides Condition rs3105749 rs3105749 SLC22A3

What the study found

Who was studied 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.022 lower; p = 4 × 10−9.

Where it sits Chromosome 6, band 6q25.3 — in an intron of SLC22A3.

What each result means

A/A No copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3105749

What is rs3105749?

rs3105749 is a single position in the genome, in or near the SLC22A3 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3105749 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

Does having rs3105749 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3105749 come from?

GWAS Catalog, Nat Genet 2018, PMID:29507422. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Triglycerides (rs3105749). MyGeneLog™. https://www.mygenelog.com/variants/rs3105749

← See all variants