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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 37,772 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 7.39 z score lower; p = 1 × 10−13.
Where it sits Chromosome X, band Xq28 — in an intron of VBP1.
What each result means
C/CNo copy of the version the research linked to Surface area (left total surface). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Surface area (left total surface). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Surface area (left total surface). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science advances · 2025 · PMID 39854466 · open access
Questions about rs3105280
What is rs3105280?
rs3105280 is a single position in the genome, in or near the VBP1 gene. Published research associates it with surface area (left total surface). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3105280 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3105280 come from?
GWAS Catalog, Science advances 2025, PMID:39854466. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 312Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon1Apple0China (ByteDance, Huawei, Baidu…)0Others2Total3Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Surface area (left total surface) (rs3105280). MyGeneLog™. https://www.mygenelog.com/variants/rs3105280