0 20112313Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others13Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 627,215 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals.
The effect
The reported allele is G; the catalogue records no effect size
; p = 2 × 10−43.
How common The G allele had a frequency of about 17% in the people studied.
Where it sits Chromosome 16, band 16q24.1 — in the 5′ untranslated region of IRF8.
What each result means
A/ANo copy of the version the research linked to Neutrophil count. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Neutrophil count. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Neutrophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs305083 is a single position in the genome, in or near the IRF8 gene. Published research associates it with neutrophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs305083 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs305083 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs305083 come from?
GWAS Catalog, Cell 2020, PMID:32888493. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 20112313Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others13Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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