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End-stage coagulation

F13A1 · rs3024321

Where this position leads

Condition: Fibrinogen and Blood Clotting

rs3024321 Condition: Fibrinogen and Blood Clotting Fibrinogen and Blood Clotting Condition rs3024321 rs3024321 F13A1

What the study found

Who was studied 2,100 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.891 lower (95% confidence interval 0.82-0.96); p = 8 × 10−142.

How common The A allele had a frequency of about 68% in the people studied.

Where it sits Chromosome 6, band 6p25.1 — in an intron of F13A1.

What each result means

A/A Two copies of the version the research linked to End-stage coagulation. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to End-stage coagulation. That is a smaller link than two copies.
G/G No copy of the version the research linked to End-stage coagulation. This is the starting point the study compared everyone against.
Source

Questions about rs3024321

What is rs3024321?

rs3024321 is a single position in the genome, in or near the F13A1 gene. Published research associates it with end-stage coagulation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3024321 linked to?

On MyGeneLog this position is linked to Fibrinogen and Blood Clotting. The research behind each link, and its sources, are set out on that condition page.

Does having rs3024321 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3024321 come from?

GWAS Catalog, Ann Neurol 2013, PMID:23381943. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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End-stage coagulation (rs3024321). MyGeneLog™. https://www.mygenelog.com/variants/rs3024321

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