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Mean platelet volume during second trimester of pregnancy

SAV1 · rs3015495

What the study found

Who was studied 71,605 Chinese ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0431 lower (95% confidence interval 0.03-0.056); p = 3 × 10−10.

How common The C allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 14, band 14q22.1 — in an intron of SAV1.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Mean platelet volume during second trimester of pregnancy compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Mean platelet volume during second trimester of pregnancy.
T/T Published research associates this genotype with typical/baseline likelihood of Mean platelet volume during second trimester of pregnancy — no copies of the reported risk allele.
Source

Questions about rs3015495

What is rs3015495?

rs3015495 is a single position in the genome, in or near the SAV1 gene. Published research associates it with mean platelet volume during second trimester of pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3015495 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3015495 come from?

GWAS Catalog, Blood 2024, PMID:38064665. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean platelet volume during second trimester of pregnancy (rs3015495). MyGeneLog™. https://www.mygenelog.com/variants/rs3015495

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