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Prostate-specific antigen levels

near DNAJC1 · rs3011633

What the study found

Who was studied 85,824 European ancestry individuals, 3,509 African American or Afro-Caribbean individuals, 3,337 East Asian ancestry individuals, 3,098 Hispanic or Latin American individuals.

The effect Each copy of the C allele shifted the measure 0.04 higher (95% confidence interval 0.032-0.048); p = 6 × 10−20.

How common The C allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 10, band 10p12.31 — between genes, 71.3 kb from DNAJC1.

What each result means

C/C Two copies of the version the research linked to Prostate-specific antigen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Prostate-specific antigen levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Prostate-specific antigen levels. This is the starting point the study compared everyone against.
Source

Questions about rs3011633

What is rs3011633?

rs3011633 is a single position in the genome, in or near the near DNAJC1 gene. Published research associates it with prostate-specific antigen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3011633 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3011633 come from?

GWAS Catalog, Nature medicine 2023, PMID:37264206. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Prostate-specific antigen levels (rs3011633). MyGeneLog™. https://www.mygenelog.com/variants/rs3011633

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