Sensitive
Metabolic syndrome (bivariate traits)
LPL · rs301
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Metabolic syndrome (bivariate traits) compared to the general population. (GWAS Catalog, Diabetes 2011, PMID:21386085)
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Metabolic syndrome (bivariate traits). (GWAS Catalog, Diabetes 2011, PMID:21386085)
T/T
Published research associates this genotype with typical/baseline likelihood of Metabolic syndrome (bivariate traits) — no copies of the reported risk allele. (GWAS Catalog, Diabetes 2011, PMID:21386085)
Source
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium
Kraja AT,
Vaidya D,
Pankow JS,
Goodarzi MO,
Assimes TL,
Kullo IJ,
Sovio U,
Mathias RA,
Sun YV,
Franceschini N,
Absher D,
Li G
and 27 more — show all
Zhang Q,
Feitosa MF,
Glazer NL,
Haritunians T,
Hartikainen AL,
Knowles JW,
North KE,
Iribarren C,
Kral B,
Yanek L,
O'Reilly PF,
McCarthy MI,
Jaquish C,
Couper DJ,
Chakravarti A,
Psaty BM,
Becker LC,
Province MA,
Boerwinkle E,
Quertermous T,
Palotie L,
Jarvelin MR,
Becker DM,
Kardia SL,
Rotter JI,
Chen YD,
Borecki IB
Diabetes · 2011 · PMID 21386085 · open access
Questions about rs301
What is rs301?
rs301 is a single position in the genome, in or near the LPL gene. Published research associates it with metabolic syndrome (bivariate traits). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs301 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs301 come from?
GWAS Catalog, Diabetes 2011, PMID:21386085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants