Standard

Medication use (anti-inflammatory and antirheumatic products, non-steroids)

STAT6 · rs3001426

Where this position leads

Condition: Medication Use as a Genetic Trait

rs3001426 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs3001426 rs3001426 STAT6

What the study found

Who was studied 74,150 European ancestry cases, 90,370 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.0562 lower (95% confidence interval 0.042-0.07); p = 1 × 10−15.

How common The C allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 12, band 12q13.3 — inside STAT6.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (anti-inflammatory and antirheumatic products, non-steroids) compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (anti-inflammatory and antirheumatic products, non-steroids).
T/T Published research associates this genotype with typical/baseline likelihood of Medication use (anti-inflammatory and antirheumatic products, non-steroids) — no copies of the reported risk allele.
Source

Questions about rs3001426

What is rs3001426?

rs3001426 is a single position in the genome, in or near the STAT6 gene. Published research associates it with medication use (anti-inflammatory and antirheumatic products, non-steroids). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3001426 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs3001426 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3001426 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Medication use (anti-inflammatory and antirheumatic products, non-steroids) (rs3001426). MyGeneLog™. https://www.mygenelog.com/variants/rs3001426

← See all variants