Standard

Self-reported math ability (MTAG)

near FOXO6 · rs2997341

Where this position leads

Condition: Educational Attainment

rs2997341 Condition: Educational Attainment Educational Attainment Condition rs2997341 rs2997341 near FOXO6

What the study found

Who was studied 670,471 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0155 lower (95% confidence interval 0.012-0.019); p = 2 × 10−15.

How common The T allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 1, band 1p34.2 — between genes, 26.7 kb from FOXO6.

What each result means

C/C No copy of the version the research linked to Self-reported math ability (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Self-reported math ability (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Self-reported math ability (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2997341

What is rs2997341?

rs2997341 is a single position in the genome, in or near the near FOXO6 gene. Published research associates it with self-reported math ability (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2997341 linked to?

On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.

Does having rs2997341 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2997341 come from?

GWAS Catalog, Nature genetics 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Self-reported math ability (MTAG) (rs2997341). MyGeneLog™. https://www.mygenelog.com/variants/rs2997341

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