Standard
Bone properties (heel)
ESR1 · rs2982552
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Bone properties (heel) — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Bone properties (heel).
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Bone properties (heel) compared to the general population.
Source
Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium
Moayyeri A,
Hsu YH,
Karasik D,
Estrada K,
Xiao SM,
Nielson C,
Srikanth P,
Giroux S,
Wilson SG,
Zheng HF,
Smith AV,
Pye SR
and 118 more — show all
Leo PJ,
Teumer A,
Hwang JY,
Ohlsson C,
McGuigan F,
Minster RL,
Hayward C,
Olmos JM,
Lyytikäinen LP,
Lewis JR,
Swart KM,
Masi L,
Oldmeadow C,
Holliday EG,
Cheng S,
van Schoor NM,
Harvey NC,
Kruk M,
del Greco M F,
Igl W,
Trummer O,
Grigoriou E,
Luben R,
Liu CT,
Zhou Y,
Oei L,
Medina-Gomez C,
Zmuda J,
Tranah G,
Brown SJ,
Williams FM,
Soranzo N,
Jakobsdottir J,
Siggeirsdottir K,
Holliday KL,
Hannemann A,
Go MJ,
Garcia M,
Polasek O,
Laaksonen M,
Zhu K,
Enneman AW,
McEvoy M,
Peel R,
Sham PC,
Jaworski M,
Johansson Å,
Hicks AA,
Pludowski P,
Scott R,
Dhonukshe-Rutten RA,
van der Velde N,
Kähönen M,
Viikari JS,
Sievänen H,
Raitakari OT,
González-Macías J,
Hernández JL,
Mellström D,
Ljunggren O,
Cho YS,
Völker U,
Nauck M,
Homuth G,
Völzke H,
Haring R,
Brown MA,
McCloskey E,
Nicholson GC,
Eastell R,
Eisman JA,
Jones G,
Reid IR,
Dennison EM,
Wark J,
Boonen S,
Vanderschueren D,
Wu FC,
Aspelund T,
Richards JB,
Bauer D,
Hofman A,
Khaw KT,
Dedoussis G,
Obermayer-Pietsch B,
Gyllensten U,
Pramstaller PP,
Lorenc RS,
Cooper C,
Kung AW,
Lips P,
Alen M,
Attia J,
Brandi ML,
de Groot LC,
Lehtimäki T,
Riancho JA,
Campbell H,
Liu Y,
Harris TB,
Akesson K,
Karlsson M,
Lee JY,
Wallaschofski H,
Duncan EL,
O'Neill TW,
Gudnason V,
Spector TD,
Rousseau F,
Orwoll E,
Cummings SR,
Wareham NJ,
Rivadeneira F,
Uitterlinden AG,
Prince RL,
Kiel DP,
Reeve J,
Kaptoge SK
Human molecular genetics · 2014 · PMID 24430505
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs2982552
What is rs2982552?
rs2982552 is a single position in the genome, in or near the ESR1 gene. Published research associates it with bone properties (heel). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs2982552?
Subjects that appear in the title or abstract of the same papers as this rsID include bones and fractures (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs2982552 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2982552 come from?
GWAS Catalog, Hum Mol Genet 2014, PMID:24430505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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