A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Breast cancer compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Breast cancer.
G/GPublished research associates this genotype with typical/baseline likelihood of Breast cancer — no copies of the reported risk allele.
rs2981582 is a single position in the genome, in or near the FGFR2 gene. Published research associates it with breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2981582 linked to?
On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs2981582 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2981582 come from?
GWAS Catalog, Hum Mol Genet 2016, PMID:27354352. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.