Gene Knowledge Graph
UTC
Sensitive

Type ii diabetes

LINC02950 · rs2980766

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 16,677 South Asian ancestry cases, 33,856 South Asian ancestry controls; replicated in 231,420 European ancestry individuals.

The effect Each copy of the C allele carried 1.04 times the odds of Type ii diabetes (95% confidence interval 1.03-1.05); p = 8 × 10−11.

How common The C allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 8, band 8p23.1 — in an intron of LINC02950.

What each result means

C/C Two copies of the version the research linked to Type ii diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Type ii diabetes. That is a smaller link than two copies.
T/T No copy of the version the research linked to Type ii diabetes. This is the starting point the study compared everyone against.
Source
Identification of genetic effects underlying type 2 diabetes in South Asian and European populations
Loh M, Zhang W, Ng HK, Schmid K, Lamri A, Tong L, Ahmad M, Lee JJ, Ng MCY, Petty LE, Spracklen CN, Takeuchi F
and 35 more — show all
Islam MT, Jasmine F, Kasturiratne A, Kibriya M, Mohlke KL, Paré G, Prasad G, Shahriar M, Chee ML, de Silva HJ, Engert JC, Gerstein HC, Mani KR, Sabanayagam C, Vujkovic M, Wickremasinghe AR, Wong TY, Yajnik CS, Yusuf S, Ahsan H, Bharadwaj D, Anand SS, Below JE, Boehnke M, Bowden DW, Chandak GR, Cheng CY, Kato N, Mahajan A, Sim X, McCarthy MI, Morris AP, Kooner JS, Saleheen D, Chambers JC
Communications biology · 2022 · PMID 35393509 · open access

Questions about rs2980766

What is rs2980766?

rs2980766 is a single position in the genome, in or near the LINC02950 gene. Published research associates it with type ii diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2980766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2980766 come from?

GWAS Catalog, Communications biology 2022, PMID:35393509. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type ii diabetes (rs2980766). MyGeneLog™. https://www.mygenelog.com/variants/rs2980766

← See all variants