Standard

QT interval

KCNH2 · rs2968863

Where this position leads

Condition: QT Interval and Drug-Induced Long QT

rs2968863 Condition: QT Interval and Drug-Induced Long QT QT Interval and Drug-Induced Long QT Condition rs2968863 rs2968863 KCNH2

What the study found

Who was studied 15,842 European ancestry individuals; replicated in up to 13,602 individuals.

The effect Each copy of the T allele shifted the measure 1.35 ms lower (95% confidence interval 0.90-1.80); p = 2 × 10−15.

How common The T allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 7, band 7q36.1 — between genes, 18 kb from KCNH2.

What each result means

C/C No copy of the version the research linked to QT interval. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to QT interval. That is a smaller link than two copies.
T/T Two copies of the version the research linked to QT interval. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2968863

What is rs2968863?

rs2968863 is a single position in the genome, in or near the KCNH2 gene. Published research associates it with qt interval. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2968863 linked to?

On MyGeneLog this position is linked to QT Interval and Drug-Induced Long QT. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs2968863?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2968863 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2968863 come from?

GWAS Catalog, Nat Genet 2009, PMID:19305409. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

QT interval (rs2968863). MyGeneLog™. https://www.mygenelog.com/variants/rs2968863

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