1 1011215Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot1Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others5Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0139 higher (95% confidence interval 0.011-0.017); p = 2 × 10−17.
Where it sits Chromosome 5, band 5q33.3 — in an intron of LINC02227.
What each result means
A/ATwo copies of the version the research linked to Diastolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Diastolic blood pressure. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Diastolic blood pressure. This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40436827 · open access
Questions about rs2963446
What is rs2963446?
rs2963446 is a single position in the genome, in or near the LINC02227 gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2963446 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs2963446 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2963446 come from?
GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 1011215Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot1Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others5Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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