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Body mass index

TRPS1 · rs2960151

Where this position leads

Conditions: Waist-to-Hip Ratio (Body Fat Distribution), Obesity and Body Weight

rs2960151 Condition: Waist-to-Hip Ratio (Body Fat Distribution) Waist-to-Hip Ratio (Body Fat Distri… Condition Condition: Obesity and Body Weight Obesity and Body Weight Condition rs2960151 rs2960151 TRPS1

What the study found

Who was studied 374,756 European ancestry male individuals.

The effect Each copy of the A allele shifted the measure 0.0208 higher (95% confidence interval 0.016-0.025); p = 2 × 10−20.

How common The A allele had a frequency of about 76% in the people studied.

Where it sits Chromosome 8, band 8q23.3 — inside TRPS1.

What each result means

A/A Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
C/C No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs2960151

What is rs2960151?

rs2960151 is a single position in the genome, in or near the TRPS1 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2960151 linked to?

On MyGeneLog this position is linked to Waist-to-Hip Ratio (Body Fat Distribution), Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs2960151 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2960151 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs2960151). MyGeneLog™. https://www.mygenelog.com/variants/rs2960151

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