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Gestational age at birth (maternal effect)

EEFSEC · rs2955117

What the study found

Who was studied 43,568 European ancestry mothers; replicated in 8,643 European ancestry mothers.

The effect Each copy of the A allele shifted the measure 0.911 higher; p = 9 × 10−15.

How common The A allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 3, band 3q21.3 — in an intron of EEFSEC.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Gestational age at birth (maternal effect) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Gestational age at birth (maternal effect).
G/G Published research associates this genotype with typical/baseline likelihood of Gestational age at birth (maternal effect) — no copies of the reported risk allele.
Source

Questions about rs2955117

What is rs2955117?

rs2955117 is a single position in the genome, in or near the EEFSEC gene. Published research associates it with gestational age at birth (maternal effect). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2955117 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2955117 come from?

GWAS Catalog, N Engl J Med 2017, PMID:28877031. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Gestational age at birth (maternal effect) (rs2955117). MyGeneLog™. https://www.mygenelog.com/variants/rs2955117

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