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Triglycerides

TRIB1 · rs2954029

Where this position leads

Condition: High Triglycerides

rs2954029 Condition: High Triglycerides High Triglycerides Condition Topic: Heart and circulation Heart and circulation Topic rs2954029 rs2954029 TRIB1

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied 19,840 European ancestry individuals; replicated in Up to 20,623 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.11 s.d. lower (95% confidence interval 0.07-0.15); p = 3 × 10−19.

How common The T allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 8, band 8q24.13 — in an intron of TRIB1AL.

What each result means

A/A No copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2954029

What is rs2954029?

rs2954029 is a single position in the genome, in or near the TRIB1 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2954029 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs2954029?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (5 papers), blood sugar and insulin (2 papers), cholesterol and blood fats (2 papers), exercise and muscle (2 papers), sleep and insomnia (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2954029 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2954029 come from?

GWAS Catalog, Nat Genet 2008, PMID:19060906. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Triglycerides (rs2954029). MyGeneLog™. https://www.mygenelog.com/variants/rs2954029

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