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Body mass index

near RASA2 · rs295300

Where this position leads

Condition: Childhood Body Mass Index

rs295300 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs295300 rs295300 near RASA2

What the study found

Who was studied 153,950 Korean ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0287 higher (95% confidence interval 0.022-0.036); p = 4 × 10−15.

How common The A allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 3, band 3q23 — between genes, 4.2 kb from RASA2.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Body mass index compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Body mass index.
G/G Published research associates this genotype with typical/baseline likelihood of Body mass index — no copies of the reported risk allele.
Source
Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures
Jee YH, Wang Y, Jung KJ, Lee JY, Kimm H, Duan R, Price AL, Martin AR, Kraft P
Nature communications · 2025 · PMID 40436827 · open access

Questions about rs295300

What is rs295300?

rs295300 is a single position in the genome, in or near the near RASA2 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs295300 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs295300 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs295300 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs295300). MyGeneLog™. https://www.mygenelog.com/variants/rs295300

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