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Postprandial small VLDL particle concentration

LPL · rs295

What the study found

The effect Each copy of the C allele shifted the measure 0.224 mmol/l lower (95% confidence interval 0.18-0.27); p = 2 × 10−19.

How common The C allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 8, band 8p21.3 — in an intron of LPL.

What each result means

A/A No copy of the version the research linked to Postprandial small VLDL particle concentration. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Postprandial small VLDL particle concentration. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Postprandial small VLDL particle concentration. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs295

What is rs295?

rs295 is a single position in the genome, in or near the LPL gene. Published research associates it with postprandial small vldl particle concentration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs295 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs295 come from?

GWAS Catalog, Diabetes 2021, PMID:34610981. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Postprandial small VLDL particle concentration (rs295). MyGeneLog™. https://www.mygenelog.com/variants/rs295

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