Standard

Gout (PheCode 274.1)

HNF4G · rs2941470

Where this position leads

Condition: Gout

rs2941470 Condition: Gout Gout Condition rs2941470 rs2941470 HNF4G

What the study found

Who was studied 14,437 African American or Afro-Caribbean cases, 103,731 African American or Afro-Caribbean controls, 3,643 Hispanic or Latin American cases, 55,120 Hispanic or Latin American controls, 1,243 East Asian ancestry cases, 5,416 East Asian ancestry controls, 42,034 European ancestry cases, 397,989 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.0603 lower (95% confidence interval 0.046-0.074); p = 2 × 10−15.

How common The G allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 8, band 8q21.13 — in an intron of HNF4G.

What each result means

A/A No copy of the version the research linked to Gout (PheCode 274.1). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Gout (PheCode 274.1). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Gout (PheCode 274.1). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2941470

What is rs2941470?

rs2941470 is a single position in the genome, in or near the HNF4G gene. Published research associates it with gout (phecode 274.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2941470 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs2941470 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2941470 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Gout (PheCode 274.1) (rs2941470). MyGeneLog™. https://www.mygenelog.com/variants/rs2941470

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