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Uric acid levels

near HNF4G · rs2941422

What the study found

Who was studied 153,950 Korean ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0368 higher (95% confidence interval 0.031-0.043); p = 5 × 10−35.

How common The T allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 8, band 8q21.13 — between genes, 40.8 kb from HNF4G.

What each result means

C/C No copy of the version the research linked to Uric acid levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Uric acid levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Uric acid levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2941422

What is rs2941422?

rs2941422 is a single position in the genome, in or near the near HNF4G gene. Published research associates it with uric acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2941422 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2941422 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Uric acid levels (rs2941422). MyGeneLog™. https://www.mygenelog.com/variants/rs2941422

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