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Body mass index (MTAG)

PPP1R3B-DT · rs2929459

What the study found

Who was studied 694,649 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0159 higher (95% confidence interval 0.012-0.02); p = 4 × 10−15.

Where it sits Chromosome 8, band 8p23.1 — inside PPP1R3B-DT.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Body mass index (MTAG) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Body mass index (MTAG).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Body mass index (MTAG) compared to the general population.
Source

Questions about rs2929459

What is rs2929459?

rs2929459 is a single position in the genome, in or near the PPP1R3B-DT gene. Published research associates it with body mass index (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2929459 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2929459 come from?

GWAS Catalog, Nature communications 2022, PMID:36376304. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body mass index (MTAG) (rs2929459). MyGeneLog™. https://www.mygenelog.com/variants/rs2929459

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