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Sphingomyelins (FA20:1) (Model 2)

CERS4 · rs2927726

What the study found

Who was studied 7,125 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.173 higher; p = 3 × 10−26.

Where it sits Chromosome 19, band 19p13.2 — in an intron of CERS4.

What each result means

C/C No copy of the version the research linked to Sphingomyelins (FA20:1) (Model 2). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Sphingomyelins (FA20:1) (Model 2). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Sphingomyelins (FA20:1) (Model 2). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2927726

What is rs2927726?

rs2927726 is a single position in the genome, in or near the CERS4 gene. Published research associates it with sphingomyelins (fa20:1) (model 2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2927726 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2927726 come from?

GWAS Catalog, Nature communications 2026, PMID:42069741. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sphingomyelins (FA20:1) (Model 2) (rs2927726). MyGeneLog™. https://www.mygenelog.com/variants/rs2927726

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