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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 3,385 Japanese ancestry individuals; replicated in 2,885 Japanese ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.143 higher (95% confidence interval 0.1-0.18); p = 4 × 10−27.
How common The T allele had a frequency of about 39% in the people studied.
Where it sits Chromosome 8, band 8q24.3 — in a regulatory region of PSCA.
What each result means
C/CNo copy of the version the research linked to Pepsinogen I/II ratio. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Pepsinogen I/II ratio. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Pepsinogen I/II ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs2920283 is a single position in the genome, in or near the PSCA gene. Published research associates it with pepsinogen i/ii ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2920283 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2920283 come from?
GWAS Catalog, Carcinogenesis 2019, PMID:30753327. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Pepsinogen I/II ratio (rs2920283). MyGeneLog™. https://www.mygenelog.com/variants/rs2920283