Standard

HDL cholesterol levels

DAB2 · rs2910949

What the study found

Who was studied 403,943 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0134 lower (95% confidence interval 0.0095-0.0173); p = 2 × 10−11.

How common The T allele had a frequency of about 65% in the people studied.

Where it sits Chromosome 5, band 5p13.1 — in an intron of LINC02104.

What each result means

G/G No copy of the version the research linked to HDL cholesterol levels. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to HDL cholesterol levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2910949

What is rs2910949?

rs2910949 is a single position in the genome, in or near the DAB2 gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2910949 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2910949 come from?

GWAS Catalog, PLoS medicine 2020, PMID:32203549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

HDL cholesterol levels (rs2910949). MyGeneLog™. https://www.mygenelog.com/variants/rs2910949

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