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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 12,298 Chinese ancestry cases, 69,440 Chinese ancestry controls.
The effect
Each copy of the G allele carried 0.90 times the odds of ICD10 I10: Essential (primary) hypertension (95% confidence interval 0.875-0.932); p = 4 × 10−10.
How common The G allele had a frequency of about 43% in the people studied.
Where it sits Chromosome 4, band 4q21.21 — between genes, 24.9 kb from FGF5.
What each result means
A/ANo copy of the version the research linked to ICD10 I10: Essential (primary) hypertension. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to ICD10 I10: Essential (primary) hypertension. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to ICD10 I10: Essential (primary) hypertension. That is the strongest link of the three results. A link in a study is not a diagnosis.
Cell genomics · 2023 · PMID 37601966 · open access
Questions about rs2903657
What is rs2903657?
rs2903657 is a single position in the genome, in or near the near FGF5 gene. Published research associates it with icd10 i10: essential (primary) hypertension. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2903657 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2903657 come from?
GWAS Catalog, Cell genomics 2023, PMID:37601966. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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