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Frozen shoulder

WNT7B · rs28971325

What the study found

Who was studied 627,998 European ancestry individuals.

The effect Each copy of the A allele carried 1.21 times the odds of Frozen shoulder (95% confidence interval 1.25-1.18); p = 8 × 10−37.

How common The A allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 22, band 22q13.31 — in an intron of WNT7B.

What each result means

A/A Two copies of the version the research linked to Frozen shoulder. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Frozen shoulder. That is a smaller link than two copies.
G/G No copy of the version the research linked to Frozen shoulder. This is the starting point the study compared everyone against.
Source

Questions about rs28971325

What is rs28971325?

rs28971325 is a single position in the genome, in or near the WNT7B gene. Published research associates it with frozen shoulder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs28971325 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28971325 come from?

GWAS Catalog, GWAS Catalog n.d., PMID:34111113. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Frozen shoulder (rs28971325). MyGeneLog™. https://www.mygenelog.com/variants/rs28971325

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