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Total bilirubin levels

WNT2 · rs2896218

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0144 lower (95% confidence interval 0.011-0.018); p = 5 × 10−17.

Where it sits Chromosome 7, band 7q31.2 — in an intron of WNT2.

What each result means

A/A Two copies of the version the research linked to Total bilirubin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Total bilirubin levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Total bilirubin levels. This is the starting point the study compared everyone against.
Source

Questions about rs2896218

What is rs2896218?

rs2896218 is a single position in the genome, in or near the WNT2 gene. Published research associates it with total bilirubin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2896218 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2896218 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total bilirubin levels (rs2896218). MyGeneLog™. https://www.mygenelog.com/variants/rs2896218

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