Sensitive
Myocardial infarction
9p21 · rs2891168
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Myocardial infarction — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Myocardial infarction.
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Myocardial infarction compared to the general population.
Source
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease
Nikpay M,
Goel A,
Won HH,
Hall LM,
Willenborg C,
Kanoni S,
Saleheen D,
Kyriakou T,
Nelson CP,
Hopewell JC,
Webb TR,
Zeng L
and 139 more — show all
Dehghan A,
Alver M,
Armasu SM,
Auro K,
Bjonnes A,
Chasman DI,
Chen S,
Ford I,
Franceschini N,
Gieger C,
Grace C,
Gustafsson S,
Huang J,
Hwang SJ,
Kim YK,
Kleber ME,
Lau KW,
Lu X,
Lu Y,
Lyytikäinen LP,
Mihailov E,
Morrison AC,
Pervjakova N,
Qu L,
Rose LM,
Salfati E,
Saxena R,
Scholz M,
Smith AV,
Tikkanen E,
Uitterlinden A,
Yang X,
Zhang W,
Zhao W,
de Andrade M,
de Vries PS,
van Zuydam NR,
Anand SS,
Bertram L,
Beutner F,
Dedoussis G,
Frossard P,
Gauguier D,
Goodall AH,
Gottesman O,
Haber M,
Han BG,
Huang J,
Jalilzadeh S,
Kessler T,
König IR,
Lannfelt L,
Lieb W,
Lind L,
Lindgren CM,
Lokki ML,
Magnusson PK,
Mallick NH,
Mehra N,
Meitinger T,
Memon FU,
Morris AP,
Nieminen MS,
Pedersen NL,
Peters A,
Rallidis LS,
Rasheed A,
Samuel M,
Shah SH,
Sinisalo J,
Stirrups KE,
Trompet S,
Wang L,
Zaman KS,
Ardissino D,
Boerwinkle E,
Borecki IB,
Bottinger EP,
Buring JE,
Chambers JC,
Collins R,
Cupples LA,
Danesh J,
Demuth I,
Elosua R,
Epstein SE,
Esko T,
Feitosa MF,
Franco OH,
Franzosi MG,
Granger CB,
Gu D,
Gudnason V,
Hall AS,
Hamsten A,
Harris TB,
Hazen SL,
Hengstenberg C,
Hofman A,
Ingelsson E,
Iribarren C,
Jukema JW,
Karhunen PJ,
Kim BJ,
Kooner JS,
Kullo IJ,
Lehtimäki T,
Loos RJF,
Melander O,
Metspalu A,
März W,
Palmer CN,
Perola M,
Quertermous T,
Rader DJ,
Ridker PM,
Ripatti S,
Roberts R,
Salomaa V,
Sanghera DK,
Schwartz SM,
Seedorf U,
Stewart AF,
Stott DJ,
Thiery J,
Zalloua PA,
O'Donnell CJ,
Reilly MP,
Assimes TL,
Thompson JR,
Erdmann J,
Clarke R,
Watkins H,
Kathiresan S,
McPherson R,
Deloukas P,
Schunkert H,
Samani NJ,
Farrall M
Nature genetics · 2015 · PMID 26343387 · open access
Questions about rs2891168
What is rs2891168?
rs2891168 is a single position in the genome, in or near the 9p21 gene. Published research associates it with myocardial infarction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2891168 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2891168 come from?
GWAS Catalog, Nat Genet 2015, PMID:26343387. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants