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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 731 Japanese ancestry cases, 846 Japanese ancestry controls.
The effect
Each copy of the G allele carried 0.44 times the odds of HTLV-1 associated myelopathy (95% confidence interval 0.33-0.58); p = 1 × 10−8.
How common The G allele had a frequency of about 95% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — between genes, 6.6 kb from HLA-DRA.
What each result means
A/ANo copy of the version the research linked to HTLV-1 associated myelopathy. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to HTLV-1 associated myelopathy. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to HTLV-1 associated myelopathy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Proceedings of the National Academy of Sciences of the United States of America · 2021 · PMID 33649182 · open access
Questions about rs28895103
What is rs28895103?
rs28895103 is a single position in the genome, in or near the near HLA-DRA gene. Published research associates it with htlv-1 associated myelopathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs28895103 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28895103 come from?
GWAS Catalog, Proceedings of the National Academy of Sciences of the United States of America 2021, PMID:33649182. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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