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Urinary albumin-to-creatinine ratio

TYRO3 · rs28844285

What the study found

Who was studied 437,027 European ancestry individuals; replicated in 60,130 individuals.

The effect Each copy of the T allele shifted the measure 0.014 higher (95% confidence interval 0.01-0.018); p = 1 × 10−11.

How common The T allele had a frequency of about 60% in the people studied.

Where it sits Chromosome 15, band 15q15.1 — between genes, 3.9 kb from TYRO3.

What each result means

C/C No copy of the version the research linked to Urinary albumin-to-creatinine ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Urinary albumin-to-creatinine ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Urinary albumin-to-creatinine ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs28844285

What is rs28844285?

rs28844285 is a single position in the genome, in or near the TYRO3 gene. Published research associates it with urinary albumin-to-creatinine ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs28844285 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28844285 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:31630189. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urinary albumin-to-creatinine ratio (rs28844285). MyGeneLog™. https://www.mygenelog.com/variants/rs28844285

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