Standard
Takayasu arteritis
PTK2B · rs28834970
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Takayasu arteritis compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Takayasu arteritis.
T/T
Published research associates this genotype with typical/baseline likelihood of Takayasu arteritis — no copies of the reported risk allele.
Source
Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study
Ortiz-Fernández L,
Saruhan-Direskeneli G,
Alibaz-Oner F,
Kaymaz-Tahra S,
Coit P,
Kong X,
Kiprianos AP,
Maughan RT,
Aydin SZ,
Aksu K,
Keser G,
Kamali S
and 59 more — show all
Inanc M,
Springer J,
Akar S,
Onen F,
Akkoc N,
Khalidi NA,
Koening C,
Karadag O,
Kiraz S,
Forbess L,
Langford CA,
McAlear CA,
Ozbalkan Z,
Yavuz S,
Çetin GY,
Alpay-Kanitez N,
Chung S,
Ates A,
Karaaslan Y,
McKinnon-Maksimowicz K,
Monach PA,
Ozer HTE,
Seyahi E,
Fresko I,
Cefle A,
Seo P,
Warrington KJ,
Ozturk MA,
Ytterberg SR,
Cobankara V,
Onat AM,
Duzgun N,
Bıcakcıgil M,
Yentür SP,
Lally L,
Manfredi AA,
Baldissera E,
Erken E,
Yazici A,
Kısacık B,
Kaşifoğlu T,
Dalkilic E,
Cuthbertson D,
Pagnoux C,
Sreih A,
Reales G,
Wallace C,
Wren JD,
Cunninghame-Graham DS,
Vyse TJ,
Sun Y,
Chen H,
Grayson PC,
Tombetti E,
Jiang L,
Mason JC,
Merkel PA,
Direskeneli H,
Sawalha AH
American journal of human genetics · 2021 · PMID 33308445
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs28834970
What is rs28834970?
rs28834970 is a single position in the genome, in or near the PTK2B gene. Published research associates it with takayasu arteritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs28834970?
Subjects that appear in the title or abstract of the same papers as this rsID include brain and memory (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs28834970 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28834970 come from?
GWAS Catalog, Am J Hum Genet 2020, PMID:33308445. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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