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Takayasu arteritis

PTK2B · rs28834970

Where this position leads

Condition: Takayasu Arteritis

rs28834970 Condition: Takayasu Arteritis Takayasu Arteritis Condition rs28834970 rs28834970 PTK2B

What the study found

Who was studied 286 European ancestry cases, 2,652 European ancestry controls, 76 Han Chinese ancestry cases, 889 Han Chinese ancestry controls, 46 South Asian ancestry cases, 501 South Asian ancestry controls, 683 Turkish ancestry cases, 1,721 Turkish ancestry controls.

The effect Each copy of the C allele carried 0.71 times the odds of Takayasu arteritis; p = 1 × 10−9.

Where it sits Chromosome 8, band 8p21.2 — in an intron of PTK2B.

What each result means

C/C Two copies of the version the research linked to Takayasu arteritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Takayasu arteritis. That is a smaller link than two copies.
T/T No copy of the version the research linked to Takayasu arteritis. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs28834970

What is rs28834970?

rs28834970 is a single position in the genome, in or near the PTK2B gene. Published research associates it with takayasu arteritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs28834970 linked to?

On MyGeneLog this position is linked to Takayasu Arteritis. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs28834970?

Subjects that appear in the title or abstract of the same papers as this rsID include brain and memory (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs28834970 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28834970 come from?

GWAS Catalog, Am J Hum Genet 2020, PMID:33308445. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Takayasu arteritis (rs28834970). MyGeneLog™. https://www.mygenelog.com/variants/rs28834970

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