Standard

ARHGEF5 protein levels

near OR2F1 · rs28829320

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.153 higher (95% confidence interval 0.12-0.19); p = 2 × 10−20.

How common The C allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 7, band 7q35 — between genes, 7 kb from OR2F1.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of ARHGEF5 protein levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with ARHGEF5 protein levels.
T/T Published research associates this genotype with typical/baseline likelihood of ARHGEF5 protein levels — no copies of the reported risk allele.
Source

Questions about rs28829320

What is rs28829320?

rs28829320 is a single position in the genome, in or near the near OR2F1 gene. Published research associates it with arhgef5 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs28829320 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28829320 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

ARHGEF5 protein levels (rs28829320). MyGeneLog™. https://www.mygenelog.com/variants/rs28829320

← See all variants