Sensitive

Venous thromboembolism recurrence in VTE

near SPMAP2L · rs28752105

Where this position leads

Condition: Venous Thromboembolism

rs28752105 Condition: Venous Thromboembolism Venous Thromboembolism Condition rs28752105 rs28752105 near SPMAP2L

What the study found

Who was studied 829 European ancestry female cases, 2,591 European ancestry female controls.

The effect Each copy of the A allele carried 2.95 times the odds of Venous thromboembolism recurrence in VTE (95% confidence interval 2.045845-4.252183); p = 7 × 10−9.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 4, band 4q12 — between genes, 15.1 kb from SPMAP2L.

What each result means

A/A Two copies of the version the research linked to Venous thromboembolism recurrence in VTE. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Venous thromboembolism recurrence in VTE. That is a smaller link than two copies.
T/T No copy of the version the research linked to Venous thromboembolism recurrence in VTE. This is the starting point the study compared everyone against.
Source

Questions about rs28752105

What is rs28752105?

rs28752105 is a single position in the genome, in or near the near SPMAP2L gene. Published research associates it with venous thromboembolism recurrence in vte. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs28752105 linked to?

On MyGeneLog this position is linked to Venous Thromboembolism. The research behind each link, and its sources, are set out on that condition page.

Does having rs28752105 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28752105 come from?

GWAS Catalog, Blood 2025, PMID:40811855. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Venous thromboembolism recurrence in VTE (rs28752105). MyGeneLog™. https://www.mygenelog.com/variants/rs28752105

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