Sex hormone-binding globulin levels adjusted for BMI
near PDGFC · rs28730491
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 368,929 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.00875 higher (95% confidence interval 0.007-0.0105); p = 3 × 10−24.
How common The C allele had a frequency of about 32% in the people studied.
Where it sits Chromosome 4, band 4q32.1 — between genes, 0.3 kb from PDGFC.
What each result means
C/CTwo copies of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. This is the starting point the study compared everyone against.
Nature medicine · 2020 · PMID 32042192 · open access
Questions about rs28730491
What is rs28730491?
rs28730491 is a single position in the genome, in or near the near PDGFC gene. Published research associates it with sex hormone-binding globulin levels adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs28730491 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28730491 come from?
GWAS Catalog, Nature medicine 2020, PMID:32042192. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Sex hormone-binding globulin levels adjusted for BMI (rs28730491). MyGeneLog™. https://www.mygenelog.com/variants/rs28730491