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Who was studied 84,036 European ancestry headache cases, 335,552 European ancestry controls without headache, 400,837 European ancestry indviduals with HbA1c.
The effect
The reported allele is A; the catalogue records no effect size
; p = 1 × 10−10.
Where it sits Chromosome 7, band 7p22.3 — in an intron of MAD1L1.
What each result means
A/ATwo copies of the version the research linked to Headache or HbA1c levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Headache or HbA1c levels. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Headache or HbA1c levels. This is the starting point the study compared everyone against.
Human genetics · 2023 · PMID 36808568 · open access
Questions about rs28728306
What is rs28728306?
rs28728306 is a single position in the genome, in or near the MAD1L1 gene. Published research associates it with headache or hba1c levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs28728306 linked to?
On MyGeneLog this position is linked to Headache. The research behind each link, and its sources, are set out on that condition page.
Does having rs28728306 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28728306 come from?
GWAS Catalog, Human genetics 2023, PMID:36808568. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Headache or HbA1c levels (rs28728306). MyGeneLog™. https://www.mygenelog.com/variants/rs28728306