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Eosinophil count

HLA-DQB1 · rs28724235

What the study found

Who was studied 234,763 European ancestry individuals; replicated in 100,553 European ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 1 × 10−16.

How common The T allele had a frequency of about 93% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — in an intron of HLA-DQB1.

What each result means

C/C No copy of the version the research linked to Eosinophil count. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Eosinophil count. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Eosinophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs28724235

What is rs28724235?

rs28724235 is a single position in the genome, in or near the HLA-DQB1 gene. Published research associates it with eosinophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs28724235 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28724235 come from?

GWAS Catalog, American journal of human genetics 2021, PMID:34469753. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Eosinophil count (rs28724235). MyGeneLog™. https://www.mygenelog.com/variants/rs28724235

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