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Pulse rate (UKB data field 102)

near TM6SF1 · rs28711295

Where this position leads

Condition: Celiac Disease

rs28711295 Condition: Celiac Disease Celiac Disease Condition rs28711295 rs28711295 near TM6SF1

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0136 lower (95% confidence interval 0.0094-0.0177); p = 1 × 10−11.

How common The T allele had a frequency of about 43% in the people studied.

Where it sits Chromosome 15, band 15q25.2 — between genes, 7.3 kb from TM6SF1.

What each result means

A/A No copy of the version the research linked to Pulse rate (UKB data field 102). This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Pulse rate (UKB data field 102). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Pulse rate (UKB data field 102). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs28711295

What is rs28711295?

rs28711295 is a single position in the genome, in or near the near TM6SF1 gene. Published research associates it with pulse rate (ukb data field 102). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs28711295 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs28711295 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28711295 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Pulse rate (UKB data field 102) (rs28711295). MyGeneLog™. https://www.mygenelog.com/variants/rs28711295

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