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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,648 Chinese ancestry cases, 68,140 Chinese ancestry controls.
The effect
Each copy of the A allele carried 1.78 times the odds of Overt hyperthyroidism in pregnancy (95% confidence interval 1.62-1.96); p = 5 × 10−32.
How common The A allele had a frequency of about 26% in the people studied.
Where it sits Chromosome 15, band 15q26.1 — in an intron of LINC01586.
What each result means
A/ATwo copies of the version the research linked to Overt hyperthyroidism in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Overt hyperthyroidism in pregnancy. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Overt hyperthyroidism in pregnancy. This is the starting point the study compared everyone against.
Nature communications · 2024 · PMID 39266554 · open access
Questions about rs28687418
What is rs28687418?
rs28687418 is a single position in the genome, in or near the LINC01586 gene. Published research associates it with overt hyperthyroidism in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs28687418 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28687418 come from?
GWAS Catalog, Nature communications 2024, PMID:39266554. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Overt hyperthyroidism in pregnancy (rs28687418). MyGeneLog™. https://www.mygenelog.com/variants/rs28687418