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Hematopoietic prostaglandin D synthase levels (HPGDS.12549.33.3)

SMARCAD1-DT · rs28660345

What the study found

Who was studied 3,301 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.41 higher (95% confidence interval 0.35-0.47); p = 8 × 10−39.

How common The A allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 4, band 4q22.2 — in an intron of SMARCAD1-DT.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hematopoietic prostaglandin D synthase levels (HPGDS.12549.33.3) compared to the general population.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hematopoietic prostaglandin D synthase levels (HPGDS.12549.33.3).
T/T Published research associates this genotype with typical/baseline likelihood of Hematopoietic prostaglandin D synthase levels (HPGDS.12549.33.3) — no copies of the reported risk allele.
Source

Questions about rs28660345

What is rs28660345?

rs28660345 is a single position in the genome, in or near the SMARCAD1-DT gene. Published research associates it with hematopoietic prostaglandin d synthase levels (hpgds.12549.33.3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs28660345 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28660345 come from?

GWAS Catalog, Nature 2018, PMID:29875488. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hematopoietic prostaglandin D synthase levels (HPGDS.12549.33.3) (rs28660345). MyGeneLog™. https://www.mygenelog.com/variants/rs28660345

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