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Total lipids in small HDL (UKB data field 23573)

HLA-DRB6 · rs28646006

What the study found

Who was studied 88,329 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0357 higher (95% confidence interval 0.024-0.047); p = 4 × 10−10.

How common The T allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — inside HLA-DRB6.

What each result means

C/C No copy of the version the research linked to Total lipids in small HDL (UKB data field 23573). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Total lipids in small HDL (UKB data field 23573). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Total lipids in small HDL (UKB data field 23573). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs28646006

What is rs28646006?

rs28646006 is a single position in the genome, in or near the HLA-DRB6 gene. Published research associates it with total lipids in small hdl (ukb data field 23573). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs28646006 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28646006 come from?

GWAS Catalog, Biological psychiatry 2023, PMID:36764567. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total lipids in small HDL (UKB data field 23573) (rs28646006). MyGeneLog™. https://www.mygenelog.com/variants/rs28646006

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