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Sleep duration (short sleep)

PAX8 · rs2863957

What the study found

Who was studied 106,192 European ancestry cases, 305,742 European ancestry controls; replicated in 47,180 adults, 10,554 children or adolescents.

The effect The reported allele is C; the catalogue records no effect size ; p = 3 × 10−18.

Where it sits Chromosome 2, band 2q14.1 — in an intron of LINC02966.

What each result means

A/A No copy of the version the research linked to Sleep duration (short sleep). This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Sleep duration (short sleep). That is a smaller link than two copies.
C/C Two copies of the version the research linked to Sleep duration (short sleep). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2863957

What is rs2863957?

rs2863957 is a single position in the genome, in or near the PAX8 gene. Published research associates it with sleep duration (short sleep). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2863957 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2863957 come from?

GWAS Catalog, Nat Commun 2019, PMID:30846698. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sleep duration (short sleep) (rs2863957). MyGeneLog™. https://www.mygenelog.com/variants/rs2863957

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