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Who was studied 434,794 European ancestry female individuals.
The effect
Each copy of the A allele shifted the measure 0.0224 lower (95% confidence interval 0.019-0.026); p = 6 × 10−34.
How common The A allele had a frequency of about 70% in the people studied.
Where it sits Chromosome 11, band 11p11.2 — in an intron of MIR670HG.
What each result means
A/ATwo copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Body mass index. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Human molecular genetics · 2019 · PMID 30239722 · open access
Questions about rs2862961
What is rs2862961?
rs2862961 is a single position in the genome, in or near the near HSD17B12 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2862961 linked to?
On MyGeneLog this position is linked to Waist-to-Hip Ratio (Body Fat Distribution), Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs2862961 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2862961 come from?
GWAS Catalog, Hum Mol Genet 2018, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Body mass index (rs2862961). MyGeneLog™. https://www.mygenelog.com/variants/rs2862961