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White blood cell count

ATF6 · rs28628087

Where this position leads

Condition: Blood Cell Counts

rs28628087 Condition: Blood Cell Counts Blood Cell Counts Condition rs28628087 rs28628087 ATF6

What the study found

Who was studied 21,347 Hispanic or Latin American individuals.

The effect Each copy of the T allele shifted the measure 0.0996 higher (95% confidence interval 0.076-0.123); p = 3 × 10−17.

How common The T allele had a frequency of about 80% in the people studied.

Where it sits Chromosome 1, band 1q23.3 — inside ATF6.

What each result means

C/C No copy of the version the research linked to White blood cell count. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to White blood cell count. That is a smaller link than two copies.
T/T Two copies of the version the research linked to White blood cell count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs28628087

What is rs28628087?

rs28628087 is a single position in the genome, in or near the ATF6 gene. Published research associates it with white blood cell count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs28628087 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs28628087 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28628087 come from?

GWAS Catalog, BMC genomics 2021, PMID:34107879. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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White blood cell count (rs28628087). MyGeneLog™. https://www.mygenelog.com/variants/rs28628087

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