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Educational attainment

TAPT1-AS1 · rs28608599

Where this position leads

Condition: Educational Attainment

rs28608599 Condition: Educational Attainment Educational Attainment Condition rs28608599 rs28608599 TAPT1-AS1

What the study found

Who was studied 3,037,499 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.00731 lower (95% confidence interval 0.005-0.0096); p = 3 × 10−10.

How common The T allele had a frequency of about 72% in the people studied.

Where it sits Chromosome 4, band 4p15.32 — in an intron of TAPT1-AS1.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Educational attainment — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Educational attainment.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Educational attainment compared to the general population.
Source
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Okbay A, Wu Y, Wang N, Jayashankar H, Bennett M, Nehzati SM, Sidorenko J, Kweon H, Goldman G, Gjorgjieva T, Jiang Y, Hicks B
and 26 more — show all
Tian C, Hinds DA, Ahlskog R, Magnusson PKE, Oskarsson S, Hayward C, Campbell A, Porteous DJ, Freese J, Herd P, Watson C, Jala J, Conley D, Koellinger PD, Johannesson M, Laibson D, Meyer MN, Lee JJ, Kong A, Yengo L, Cesarini D, Turley P, Visscher PM, Beauchamp JP, Benjamin DJ, Young AI
23andMe Research Team · Social Science Genetic Association Consortium
Nature genetics · 2022 · PMID 35361970 · open access

Questions about rs28608599

What is rs28608599?

rs28608599 is a single position in the genome, in or near the TAPT1-AS1 gene. Published research associates it with educational attainment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs28608599 linked to?

On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.

Does having rs28608599 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28608599 come from?

GWAS Catalog, Nature genetics 2022, PMID:35361970. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Educational attainment (rs28608599). MyGeneLog™. https://www.mygenelog.com/variants/rs28608599

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