Sensitive
Trichloroethylene-induced hypersensitivity syndrome
MICA · rs2857281
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Trichloroethylene-induced hypersensitivity syndrome — no copies of the reported risk allele.
A/C
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Trichloroethylene-induced hypersensitivity syndrome.
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Trichloroethylene-induced hypersensitivity syndrome compared to the general population.
Source
Performance of genetic risk factors in prediction of trichloroethylene induced hypersensitivity syndrome
Dai Y,
Chen Y,
Huang H,
Zhou W,
Niu Y,
Zhang M,
Bin P,
Dong H,
Jia Q,
Huang J,
Yi J,
Liao Q
and 26 more — show all
Li H,
Teng Y,
Zang D,
Zhai Q,
Duan H,
Shen J,
He J,
Meng T,
Sha Y,
Shen M,
Ye M,
Jia X,
Xiang Y,
Huang H,
Wu Q,
Shi M,
Huang X,
Yang H,
Luo L,
Li S,
Li L,
Zhao J,
Li L,
Wang J,
Wang J,
Zheng Y
Scientific reports · 2015 · PMID 26190474 · open access
Questions about rs2857281
What is rs2857281?
rs2857281 is a single position in the genome, in or near the MICA gene. Published research associates it with trichloroethylene-induced hypersensitivity syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2857281 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2857281 come from?
GWAS Catalog, Sci Rep 2015, PMID:26190474. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants