7 4852333222224Reads by AI crawlersClaude5ChatGPT2Google · Gemini3Perplexity3Meta AI3Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others24Total48Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,999 Han Chinese ancestry male individuals; replicated in 1,496 Han Chinese ancestry male individuals.
The effect
Each copy of the G allele shifted the measure 0.08 g/L higher (95% confidence interval 0.060-0.100); p = 1 × 10−22.
How common The G allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in an intron of TNXB.
What each result means
C/CNo copy of the version the research linked to Complement C3 and C4 levels. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Complement C3 and C4 levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Complement C3 and C4 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs2857009
What is rs2857009?
rs2857009 is a single position in the genome, in or near the C4 gene. Published research associates it with complement c3 and c4 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2857009 linked to?
On MyGeneLog this position is linked to Complement C3 and C4 Levels. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs2857009?
Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs2857009 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2857009 come from?
GWAS Catalog, PLoS Genet 2012, PMID:23028341. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
7 4852333222224Reads by AI crawlersClaude5ChatGPT2Google · Gemini3Perplexity3Meta AI3Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others24Total48Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Complement C3 and C4 levels (rs2857009). MyGeneLog™. https://www.mygenelog.com/variants/rs2857009